Home Oncology • Pharmaceutical Aspects of Cancer Chemotherapy. Topics in by A. T. Florence, E. G. Salole

Pharmaceutical Aspects of Cancer Chemotherapy. Topics in by A. T. Florence, E. G. Salole

By A. T. Florence, E. G. Salole

Concentrates on these medicinal drugs utilized in chemotherapy, their equipment of program and the impact of the sickness on their motion. This publication is aimed toward somebody concerned with the meting out of cytotoxic medicinal drugs, in addition to pharmacists at any point

Show description

Read or Download Pharmaceutical Aspects of Cancer Chemotherapy. Topics in Pharmacy PDF

Similar oncology books

Improving the Quality of Cancer Clinical Trials: Workshop Summary

Scientists and clinicians search a brand new paradigm that can enhance the potency, cost-effectiveness, and total good fortune expense of melanoma medical trials, whereas retaining the top criteria of caliber. To discover cutting edge paradigms for melanoma medical trials and alternative routes to enhance their caliber, the nationwide melanoma coverage discussion board held a workshop, enhancing the standard of melanoma scientific Trials, in Washington, DC.

Methods of Cancer Diagnosis, Therapy and Prognosis Vol. 4: Colorectal Cancer

This fourth quantity within the sequence equipment of melanoma prognosis, remedy and analysis discusses quite a few methodologies for the analysis, treatment and analysis of Colorectal melanoma. either ordinary and rising remedies for this melanoma, written via professional oncologists/pathologists during this box, are integrated.

WHO Classification of Tumours of hematopoietic and lymphoid tissues 4th edition

WHO class of Tumours of Haematopoietic and Lymphoid Tissue is the 3rd quantity within the new WHO sequence on histological and genetic typing of human tumors. This authoritative, concise reference e-book covers the total variety of leukaemias and lymphomas. It presents a global general for oncologists and pathologists and may function an fundamental consultant to be used within the layout of reviews tracking reaction to remedy and medical end result.

Oral Complications of Cancer and its Management

Oral difficulties are universal in melanoma sufferers. they could be a a part of the illness itself; they could enhance because of therapy; they could accompany different signs and current as a comorbidity; they usually also can first current after the unique affliction itself has been cured. Oral signs might be advanced to regard, either fighting management of doubtless life-saving therapy, and in addition at once inflicting extra life-threatening problems.

Extra resources for Pharmaceutical Aspects of Cancer Chemotherapy. Topics in Pharmacy

Sample text

G. the lipophilic analogue of the anticancer drug cisplatin codenamed L-NDDP. Cisplatin is one of the most successful anticancer agents available, having curative potential in testicular cancer and good activity in ovarian and lung cancers, but it suffers from severe nephrotoxicity as well as the problem of pleiotropic drug resistance. However, L-NDDP is a water insoluble analogue and is almost completely inactive when administered as non-entrapped drug in a micellar suspension. Liposomal-L-NDDP is as active as cisplatin against animal tumour models, is non-cross resistant, and in dogs produces no significant renal dysfunction.

Preclinical antitumor activity of a soluble etoposide analog, BMY-40481-30. Investigational New Drugs, 8(Suppl. 1), S25-S32, 1990 Senter, P. , Schreiber, G. , Hirschberg, D. , Ashe, S. , Hellstrom, K. E. and Hellstrom, I. Enhancement of the in vitro and in vivo antitumor activities of phosphorylated mitomycin C and etoposide derivatives by monoclonal antibody -alkaline phosphatase conjugates. Cancer Research, 49, 5789-5792, 1989 Senter, P. , Saulnier, M. , Schreiber, G. , Hirschberg, D. , Brown, J.

Phillips, J. -M. and Roe, D. J. Plasma phamnacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous versus oral administration in a randomized crossover trial. Cancer Research, 47, 2723-2726, 1987 51. Clark, L. and Waxman, D. J. Oxidative metabolism of cyclophosphamide: identification of the hepatic monooxygenase catalysts of drug activation. Cancer Research, 49, 2344-2350, 1989 52. Norpoth, K. Studies on the metabolism of isophosphamide (NSC-109724) in man. Cancer Treatment Reports, 60, 437-443, 1976 53.

Download PDF sample

Rated 4.54 of 5 – based on 21 votes