By Anais Malpica MD, Elizabeth D. Euscher MD
- Stay brand new with what’s new in gynecologic pathology with an all-new bankruptcy on metastatic tumors, plus up to date references and terminology throughout.
- Focus on differential prognosis and usually encountered pitfalls of the commonest entities saw within the cervix, endometrium, and myometrium.
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Extra resources for Biopsy Interpretation of the Uterine Cervix and Corpus
Total absence of staining or staining with these characteristics: cytoplasmic only, single cells, scattered cells, and wispy) or a focal/patchy nuclear staining (Fig. 15). , a continuous strong nuclear or nuclear plus cytoplasmic staining of the basal layer with extension upward involving at least one-third of the epithelial thickness) (Fig. 16, e-Figs. 60) (12). Important caveats in the interpretation of p16 results are as follows: (a) approximately one-third of the LSILs show “block-type” positivity (14), (b) the concept of “continuous block staining” requires an “adequate” sample of properly oriented tissue that must correlate with the area of morphologic concern (12), and (c) a rare case of HSIL will fail to show the “block-type positivity” most likely due to preanalytic factors (15).
Healthcare professionals, and not the publisher, are solely responsible for the use of this work including all medical judgments and for any resulting diagnosis and treatments. Given continuous, rapid advances in medical science and health information, independent professional verification of medical diagnoses, indications, appropriate pharmaceutical selections and dosages, and treatment options should be made and healthcare professionals should consult a variety of sources. When prescribing medication, healthcare professionals are advised to consult the product information sheet (the manufacturer’s package insert) accompanying each drug to verify, among other things, conditions of use, warnings and side effects and identify any changes in dosage schedule or contraindications, particularly if the medication to be administered is new, infrequently used or has a narrow therapeutic range.
1999;18:125–129. Kling E, Kitahara S, Posligua L, et al. The 2 stromal compartments of the normal cervix with distinct immunophenotypic and histomorphologic features. Ann Diagn Pathol. 2012;16:315–322. Ferry JA, Scully RE. Mesonephric remnants, hyperplasia, and neoplasia of the uterine cervix. A study of 49 cases. Am J Surg Pathol. 1990;14:1100–1111. Ordi J, Nogales FF, Palacin A, et al. Mesonephric adenocarcinoma of the uterine corpus: CD10 expression as evidence of mesonephric differentiation.